核RNA输出因子3抗体
规格:1mg/1ml
英文名: NXF3
别名: Nuclear RNA export factor 3; NXF3; NXF3_HUMAN; OTTHUMP00000023726; OTTHUMP00000023727; TAP like protein 3; TAP-like protein 3; TAPL 3; TAPL-3; TAPL3.
分子量: 60kD
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NXF3
交叉反应:Human,
细胞定位:细胞核 细胞浆
核RNA输出因子3抗体产品介绍:background: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to 核RNA输出因子3抗体bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008] Function: May function as a tissue-specific nuclear mRNA export factor. Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Expressed at high level in testis and at low level in a small number of tissues. Similarity核RNA输出因子3抗体: Belongs to the NXF family. Contains 1 NTF2 domain. Contains 1 RRM (RNA recognition motif) domain. Gene ID: 56000 Database links: Entrez Gene: 56000 Human Omim: 300316 Human SwissProt: Q9H4D5 Human Unigene: 60386 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:核RNA输出因子3抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:染色质和核信号 转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid