核孔蛋白样蛋白2抗体
规格:1mg/1ml
英文名: NUPL2
别名: CG1; NLP1; Nucleoporin hCG1; NUPL2_HUMAN; Nucleoporin like protein 2; NUP42 homolog.
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NUPL2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
核孔蛋白样蛋白2抗体产品介绍:background: NUPL2 is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. Function: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. Subunit: Probable component of the nuclear pore complex (NPC). Interacts with nuclear export protein NXF1. Interacts with GLE1. Able to form a heterotrimer with NUP155 and GLE1 in vitro. Interacts with the HIV-1 virus proteins Rev and Vpr.核孔蛋白样蛋白2抗体 The interaction with HIV-1 Rev, a protein that mediates nuclear export of unspliced viral RNAs, suggests that its function may be bypassed by the HIV-1 virus. Subcellular Location: Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Excluded from the nucleolus. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: O-glycosylated. Similarity: 核孔蛋白样蛋白2抗体Contains 1 C3H1-type zinc finger. Gene ID: 11097 Database links: Entrez Gene: 11097 Human Entrez Gene: 231042 Mouse Entrez Gene: 499974 Rat SwissProt: O15504 Human SwissProt: Q8CIC2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:核孔蛋白样蛋白2抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:染色质和核信号 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid