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核孔蛋白样蛋白2抗体

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产品名称: 核孔蛋白样蛋白2抗体
产品型号: NUPL2
产品展商: 单克隆抗体/多克隆抗体
产品文档: 无相关文档

简单介绍

核孔蛋白样蛋白2抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。核孔蛋白样蛋白2抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。


核孔蛋白样蛋白2抗体  的详细介绍

核孔蛋白样蛋白2抗体

规格:1mg/1ml

英文名: NUPL2

别名: CG1; NLP1; Nucleoporin hCG1; NUPL2_HUMAN; Nucleoporin like protein 2; NUP42 homolog.

分子量: 45kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:Polyclonal

亚型:IgG

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human NUPL2

交叉反应:Human, Mouse, Rat,

细胞定位:细胞核

核孔蛋白样蛋白2抗体产品介绍:background: NUPL2 is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. Function: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. Subunit: Probable component of the nuclear pore complex (NPC). Interacts with nuclear export protein NXF1. Interacts with GLE1. Able to form a heterotrimer with NUP155 and GLE1 in vitro. Interacts with the HIV-1 virus proteins Rev and Vpr.核孔蛋白样蛋白2抗体 The interaction with HIV-1 Rev, a protein that mediates nuclear export of unspliced viral RNAs, suggests that its function may be bypassed by the HIV-1 virus. Subcellular Location: Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Excluded from the nucleolus. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: O-glycosylated. Similarity: 核孔蛋白样蛋白2抗体Contains 1 C3H1-type zinc finger. Gene ID: 11097 Database links: Entrez Gene: 11097 Human Entrez Gene: 231042 Mouse Entrez Gene: 499974 Rat SwissProt: O15504 Human SwissProt: Q8CIC2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品应用:核孔蛋白样蛋白2抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:染色质和核信号  信号转导  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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