NUDT5蛋白抗体
规格：1mg/1ml
英文名： NUDT5
别名： ADP sugar pyrophosphatase; ADP-sugar pyrophosphatase; hYSAH 1; hYSAH1; Nucleoside diphosphate linked moiety X motif 5; Nucleoside diphosphate linked moiety X type motif 5; Nucleoside diphosphate-linke
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NUDT5
交叉反应：Human,
细胞定位：细胞浆
NUDT5蛋白抗体产品介绍：background: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.NUDT5蛋白抗体 [provided by RefSeq, Aug 2013] Function: Hydrolyzes with similar activities ADP-ribose, ADP-mannose, and ADP-glucose. Can also hydrolyze other nucleotide sugars with low activity. Tissue Specificity: Widely expressed. Most abundant in liver. Similarity: Belongs to the Nudix hydrolase family. Contains 1 nudix hydrolase domain. Gene ID: 11164 Database links: Entrez Gene: 11164 Human Entrez Gene: 53893 Mouse Entrez NUDT5蛋白抗体Gene: 361274 Rat Omim: 609230 Human SwissProt: Q9UKK9 Human SwissProt: Q9JKX6 Mouse SwissProt: Q6AY63 Rat Unigene: 555956 Human Unigene: 251904 Mouse Unigene: 55388 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NUDT5蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid