囊泡相关膜蛋白2抗体
规格：1mg/1ml
英文名： VAMP2
别名： Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobrevin 2; VAMP 2; VAMP-2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2; VAMP2_HU
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VAMP-2 (
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
细胞定位：细胞浆 细胞膜
囊泡相关膜蛋白2抗体产品介绍：background: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]. Function: Involved in the targeting and/or fusion of transport vesicles to their target囊泡相关膜蛋白2抗体 membrane. Subunit: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Interacts with BVES and STX4 (By similarity). Interacts with VAPA and VAPB. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Note=Neuronal synaptic vesicles. Tissue Specificity: Nervous system and skeletal muscle. Similarity: Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. Gene ID: 63027囊泡相关膜蛋白2抗体 Database links: Entrez Gene: 6844 Human Entrez Gene: 22318 Mouse Entrez Gene: 24803 Rat Omim: 185881 Human SwissProt: P63027 Human SwissProt: P63044 Mouse SwissProt: P63045 Rat Unigene: 25348 Human Unigene: 28643 Mouse Unigene: 12939 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. VAMP-2是真核生物中的一种膜受体蛋白,该蛋白在真核生物的胞吐、信号传导、胞内运输和分泌等活动中起到重要作用.
囊泡相关膜蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid