线粒体NT5M抗体
规格:1mg/1ml
英文名: NT5M
别名: 3''-nucleotidase; 5''; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, mitochondrial; 5',3'-nucleotidase, mitochondrial; Deoxy-5''-nucleotidase 2; dNT-2; DNT2; mitochondrial; NT5M; NT5M_
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NT5M
交叉反应:Human, Mouse,
细胞定位:细胞核
线粒体NT5M抗体产品介绍:background: This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] Function: Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards线粒体NT5M抗体 dIMP and dGMP. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas. Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family. Database links线粒体NT5M抗体 Entrez Gene: 56953 Human SwissProt: Q9NPB1 Human Unigene: 513977 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体NT5M抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid