信号通路WNT10A抗体
规格：1mg/1ml
英文名： WNT10A
别名： wingless-type MMTV integration site family, member 10A; WNT 10A; WNT10 A; WNT10A; Protein Wnt-10a; WN10A_HUMAN.
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human WNT10A
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞外基质 分泌型蛋白
信号通路WNT10A抗体产品介绍：background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway.信号通路WNT10A抗体 This gene and the WNT6 gene are clustered in the chromosome 2q35 region. Subcellular Location: 信号通路WNT10A抗体Secreted, extracellular space, extracellular matrix. Similarity: Belongs to the Wnt family. Gene ID: 80326 Database links: Entrez Gene: 80326 Human Entrez Gene: 22409 Mouse Omim: 606268 Human SwissProt: Q9GZT5 Human SwissProt: P70701 Mouse Unigene: 121540 Human Unigene: 5130 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Wnt通路与人类多种肿瘤的发生有关,WNT10A主要用于消化系统肿瘤的研究。
信号通路WNT10A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid