NSMCE4A蛋白抗体
规格：1mg/1ml
英文名： NSMCE4A
别名： C10orf86; non-SMC element 4 homolog A (S. cerevisiae); Non-SMC element 4 homolog A; non-SMC element 4, S. cerevisiae, homolog of, A; Non-structural maintenance of chromosomes element 4 homolog A; NSE4
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NSMCE4A
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
NSMCE4A蛋白抗体细胞定位：细胞核
产品介绍：Function: Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus. Subunit: Component of the SMC5-SMC6 complex NSMCE4A蛋白抗体which consists at least of SMC5, SMC6, NSMCE2, NSMCE1, NSMCE4A or EID3 and NDNL2. NSMCE1, NSMCE4A or EID3 and NDNL2 probably form a subcomplex that bridges the head domains of the SMC5:SMC6 heterodimer. Similarity: Belongs to the NSE4 family. Database NSMCE4A蛋白抗体links: Entrez Gene: 54780 Human Entrez Gene: 67872 Mouse Entrez Gene: 293528 Rat Omim: 612987 Human SwissProt: Q9NXX6 Human Unigene: 258798 Human Unigene: 21714 Mouse Unigene: 228750 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NSMCE4A蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid