蛋白酶调解因子14抗体
规格:1mg/1ml
英文名: PSMD14
别名: 26S proteasome non-ATPase regulatory subunit 14; 26S proteasome regulatory subunit rpn11; 26S proteasome-associated PAD1 homolog 1; 26S proteasome-associated PAD1 homolog; PAD1; PAD1, yeast, homolog o
分子量: 35kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PSMD14
交叉反应:Human, Mouse,
细胞定位:细胞核 细胞浆
蛋白酶调解因子14抗体产品介绍:background: This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2. [provided by RefSeq, Feb 2012] Function: Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function 蛋白酶调解因子14抗体of the 'Lys-63'-specific deubiquitination of the proteasome is unclear. Tissue Specificity: Widely expressed. Highest levels in heart and skeletal muscle. Similarity: Belongs to the peptidase M67A family. PSMD14 subfamily. Contains 1 MPN (JAB/Mov34) domain. Gene ID: 10213 Database links: Entrez Gene: 10213 Human Entrez Gene: 59029 Mouse Entrez Gene: 311078 Rat Omim: 607173 Human SwissProt: 蛋白酶调解因子14抗体O00487 Human SwissProt: O35593 Mouse Unigene: 567410 Human Unigene: 218198 Mouse Unigene: 161794 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酶调解因子14抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学 泛素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid