胞粘蛋白4抗体
规格：1mg/1ml
英文名： PSCD4
别名： AI467541; CYH4_HUMAN; CYT4; Cyth4; Cytohesin 4; Cytohesin-4; DJ63G5.1; FLJ00017; PH; PH, SEC7 and coiled coil domain containing protein 4; Pleckstrin homology, SEC7, AND coiled coil domains protein 4;
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PSCD4
交叉反应：Human, Mouse,
细胞定位：细胞膜
胞粘蛋白4抗体产品介绍：background: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 胞粘蛋白4抗体and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar. [provided by RefSeq, Aug 2008] Function: Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF through replacement of GDP with GTP. Subcellular Location: Cell membrane. Tissue Specificity: Expressed predominantly in peripheral blood leukocytes. Similarity: Contains 1 胞粘蛋白4抗体PH domain. Contains 1 SEC7 domain. Gene ID: 27128 Database links: Entrez Gene: 27128 Human Omim: 606514 Human SwissProt: Q9UIA0 Human Unigene: 170944 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胞粘蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid