中胚层配对同源蛋白2抗体
规格:1mg/1ml
英文名: PRRX2
别名: Paired mesoderm homeobox protein 2; Paired related homeobox protein 2; paired-like homeobox gene 2; paired-like homeodomain protein PRX2; Paired-related homeobox protein 2; PMX2; Predicted NUP98/PRRX2
分子量: 27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PRRX2
交叉反应:Human, Mouse, Rat, Chicken,
细胞定位:细胞核
中胚层配对同源蛋白2抗体产品介绍:background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in ***** skin. Increases in expression of this gene during fetal but not ***** wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008] Function: May play a role in the scarless中胚层配对同源蛋白2抗体 healing of cutaneous wounds during the first two trimesters of development. Subcellular Location: Nucleus. Tissue Specificity: In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In ***** skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis. Similarity: Belongs to the paired homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 51450 Human Entrez Gene: 20204 Mouse Entrez Gene: 中胚层配对同源蛋白2抗体113931 Rat Omim: 604675 Human SwissProt: Q99811 Human SwissProt: Q06348 Mouse Unigene: 660115 Human Unigene: 1802 Mouse Unigene: 93004 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中胚层配对同源蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 发育生物学 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid