富含脯氨酸跨膜蛋白1抗体
规格:1mg/1ml
英文名: PRRT1
别名: Bat 4; Bat4; C6orf31; D17H6S54E; DAAP-218M18.1; Dispanin subfamily D member 1; DSPD1; G5b; IFITMD7; interferon induced transmembrane protein domain containing 7; NG5; ORF31; Proline-rich transmembrane
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PRRT1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Cat,
细胞定位:细胞膜
产富含脯氨酸跨膜蛋白1抗体品介绍:Subunit: Component of the outer core of AMPAR complex. AMPAR complex consists of an inner core made of 4 pore-forming GluA/GRIA proteins (GRIA1, GRIA2, GRIA3 and GRIA4) and 4 major auxiliary subunits arranged in a twofold symmetry. One of the two pairs of distinct binding sites is occupied either by CNIH2, CNIH3 or CACNG2, CACNG3. The other harbors CACNG2, CACNG3, CACNG4, CACNG8 or GSG1L. This inner core of AMPAR complex is complemented by outer core constituents binding directly to the GluA/GRIA proteins at sites distinct from the interaction sites of the inner core constituents. Outer core constituents include at least PRRT1, 富含脯氨酸跨膜蛋白1抗体PRRT2, CKAMP44/SHISA9, FRRS1L and NRN1. The proteins of the inner and outer core serve as a platform for other, more peripherally associated AMPAR constituents. Alone or in combination, these auxiliary subunits control the gating and pharmacology of the AMPAR complex and profoundly impact their biogenesis and protein processing (By similarity). Subcellular Location: Membrane. Similarity: Belongs to the富含脯氨酸跨膜蛋白1抗体 capucin family. Database links: Entrez Gene: 80863 Human Entrez Gene: 260297 Mouse Entrez Gene: 406167 Rat SwissProt: Q99946 Human SwissProt: O35449 Mouse SwissProt: Q6MG82 Rat Unigene: 549204 Human Unigene: 699821 Human Unigene: 390965 Mouse Unigene: 144293 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含脯氨酸跨膜蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 跨膜蛋白 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid