白血病相关新基因抗体
规格:1mg/1ml
英文名: Zfp91
别名: zinc finger protein 91; FKSG11; HGNC:14983; PZF; zinc finger protein 91 homolog (mouse); zinc finger protein homologous to mouse Zfp91; ZFP91_HUMAN.
分子量: 63kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Zfp91
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞核
白血病相关新基因抗体产品介绍:background: The protein encoded by ZFP91 is a member of the zinc finger family of proteins. This protein contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis Found in all the examined tissues including brain, heart, kidney, lung, liver, spleen, thymus, skeletal muscle, ovary and testis. Belongs to the krueppel C2H2-type zinc-finger protein family. Function: Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate白血病相关新基因抗体 MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis. Subunit: Interacts with MAP3K14/NIK. Subcellular Location: Nucleus. Tissue Specificity: Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family.白血病相关新基因抗体 Contains 5 C2H2-type zinc fingers. Gene ID: 80829 Database links: Entrez Gene: 80829 Human Entrez Gene: 109910 Mouse Entrez Gene: 246282 Rat SwissProt: Q96JP5 Human SwissProt: Q62511 Mouse Unigene: 524920 Human Unigene: 290924 Mouse Unigene: 1772 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产白血病相关新基因抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号 神经生物学 细胞凋亡 转录调节因子 结合蛋白 细胞分化
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid