鸟苷酸环化酶激活因子2B抗体
规格：1mg/1ml
英文名： GUCA2B
别名： Prouroguanylin GUCA2B; GCAP II; GCAP-II; Guanylate cyclase activator 2B (uroguanylin); Guanylate cyclase activator 2B; Guanylate cyclase C-activating peptide II; GUC2B_HUMAN; GUCA2B; UGN; Uroguanylin.
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GUCA2B
交叉反应：Human,
细胞定位：分泌型蛋白
鸟苷酸环化酶激活因子2B抗体产品介绍：background: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Uroguanylin is an endogenous activator of intestinal guanylate cyclase. It is a paracrine and/or autocrine regulator of intestinal water and salt transport. Uroguanylin stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Uroguanylin is involved in the regulation of intestinal fluid and electrolyte transport. Function: Endogenous activator of intestinal guanylate 鸟苷酸环化酶激活因子2B抗体cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. Subcellular Location: Secreted. Tissue Specificity: Stomach and intestine. Similarity: Belongs to the guanylin family. Database links:鸟苷酸环化酶激活因子2B抗体 Entrez Gene: 2981 Human Omim: 601271 Human SwissProt: Q16661 Human Unigene: 32966 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
鸟苷酸环化酶激活因子2B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid