蛋白磷酸酶1调节亚基3C抗体
规格：1mg/1ml
英文名： PPR3C
别名： Protein phosphatase 1 inhibitor 3C; OTTHUMP00000020089; Phosphatase 1, regulatory inhibitor subunit 5; PP1 subunit R5; ppp1r3c; PPP1R5; PPR3C_HUMAN; Protein phosphatase 1 regulatory subunit 3C; Protei
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human PPR3C
交叉反应：Human, Mouse, Rat,
细胞定位：
蛋白磷酸酶1调节亚基3C抗体产品介绍：background: This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals. [provided by RefSeq, Oct 2011] Function: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen蛋白磷酸酶1调节亚基3C抗体 breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types. Post-translational modifications: Ubiquitinated by NHLRC1/malin in a EPM2A/laforin-dependent manner. Similarity: Contains 1 蛋白磷酸酶1调节亚基3C抗体CBM21 (carbohydrate binding type-21) domain. Gene ID: 5507 Database links: Entrez Gene: 5507 Human Entrez Gene: 53412 Mouse Omim: 602999 Human SwissProt: Q9UQK1 Human SwissProt: Q7TMB3 Mouse Unigene: 303090 Human Unigene: 24724 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产蛋白磷酸酶1调节亚基3C抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid