泛素样蛋白SUMO2激活酶抗体
规格：1mg/1ml
英文名： SAE2
别名： Anthracycline associated resistance ARX; Anthracycline-associated resistance ARX; ARX; FLJ13058; HRIHFB2115; SAE 2; SAE2; SAE2_HUMAN; SUMO 1 activating enzyme subunit 2; SUMO activating enzyme subunit
分子量： 71kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SAE2
交叉反应：Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位：细胞核
泛素样蛋白SUMO2激活酶抗体产品介绍：background: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] Function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue 泛素样蛋白SUMO2激活酶抗体on UBA2/SAE2. Subcellular Location: Nucleus. Similarity: Belongs to the ubiquitin-activating E1 family. Gene ID: 10054 Database links: Entrez Gene: 10054 Human Entrez Gene: 50995 Mouse Entrez Gene: 308508 Rat Entrez Gene: 406672 Zebrafish Omim: 613295 Human SwissProt: Q9UBT2 Human SwissProt: Q9Z1F9 Mouse SwissProt: Q7SXG4 Zebrafish Unigene: 631580 Human Unigene: 27560 Mouse泛素样蛋白SUMO2激活酶抗体 Unigene: 198150 Rat Unigene: 78013 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
泛素样蛋白SUMO2激活酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid