神经视网膜特定亮氨酸拉链蛋白抗体
规格：1mg/1ml
英文名： Neural retinal specific leucine zipper/NRL
别名： D14S46E; Neural retina-specific leucine zipper protein; Neural retinal specific leucine zipper; NRL; NRL MAF; NRL_HUMAN; RP27.
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neural r
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞核
神经视网膜特定亮氨酸拉链蛋白抗体产品介绍：background: This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008] Function: Transcription factor which regulates the expression of several rod-specific genes, in cluding RHO and PDE6B. Subcellular Location: Nucleus. Tissue Specificity: Neural retina. DISEASE: Defects in NRL are the cause of retinitis pigmentosa type 27 (RP27) [MIM:162080]. RP leads to神经视网膜特定亮氨酸拉链蛋白抗体 degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP27 inheritance is autosomal神经视网膜特定亮氨酸拉链蛋白抗体 dominant. Similarity: Belongs to the bZIP family. Contains 1 bZIP domain. Gene ID: 4901 Database links: Entrez Gene: 4901 Human Entrez Gene: 18185 Mouse Omim: 162080 Human SwissProt: P54845 Human SwissProt: P54846 Mouse Unigene: 652297 Human Unigene: 20422 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经视网膜特定亮氨酸拉链蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid