神经细胞PAS结构域蛋白4抗体
规格：1mg/1ml
英文名： NPAS4
别名： bHLH PAS type transcription factor NXF; bHLHe79; bHLHe79; Class E basic helix-loop-helix protein 79; HLH-PAS transcription factor NXF; Le PAS; limbic enhanced PAS protein; neuronal PAS domain protein
分子量： 87kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NPAS4
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
神经细胞PAS结构域蛋白4抗体产品介绍：background: NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] Function: Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT. Subcellular Location: Nucleus. Tissue Specificity: Brain. 神经细胞PAS结构域蛋白4抗体Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2 PAS (PER-ARNT-SIM) domains. Gene ID: 266743 Database links: Entrez Gene: 266743 Human Entrez Gene: 225872 Mouse Entrez Gene: 266734 Rat Entrez Gene: 724016 Zebrafish Omim: 608554 Human SwissProt: Q8IUM7 Human SwissProt: Q8BGD7 Mouse SwissProt: Q8CJH6 神经细胞PAS结构域蛋白4抗体Rat SwissProt: Q1ECW2 Zebrafish Unigene: 256036 Human Unigene: 287867 Mouse Unigene: 86654 Rat Unigene: 81110 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞PAS结构域蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid