核仁蛋白12抗体
规格：1mg/1ml
英文名： NOL12/NOP25
别名： C78541; dJ37E16.7; FLJ34609; MGC3731; Nol12; NOL12_HUMAN; Nop25; Nucleolar protein 12; Nucleolar protein of 25 kDa.
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NOL12/NO
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞核
核仁蛋白12抗体产品介绍：background: Nop25 is a 213 amino acid protein that localizes to the nucleolus and is thought to bind to 28S rRNA, possibly playing a role in the processing of rRNA molecules and in the subsequent assembly and maturation of ribosomes. The gene encoding Nop25 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia 核仁蛋白12抗体Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Function: May bind to 28S rRNA. Subcellular Location: Nucleus > nucleolus. Similarity: Belongs to the RRP17 family. 核仁蛋白12抗体Database links: Entrez Gene: 79159 Human Entrez Gene: 97961 Mouse Entrez Gene: 362955 Rat SwissProt: Q9UGY1 Human SwissProt: Q8BG17 Mouse SwissProt: Q5D1Z3 Rat Unigene: 632778 Human Unigene: 157216 Mouse Unigene: 17454 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核仁蛋白12抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid