NLRP8蛋白抗体
规格：1mg/1ml
英文名： NLRP8
别名： CLR19.2; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 8; NACHT, leucine rich repeat and PYD containing 8; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-contain
分子量： 119kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NLRP8
交叉反应：Human,
细胞定位：细胞浆
NLRP8蛋白抗体产品介绍：background: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP8, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al.NLRP8蛋白抗体, 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008] Function: Involved in inflammation. Subcellular Location: Cytoplasm. Similarity: Belongs to the NLRP family. Contains 1 DAPIN domain. Contains 5 LRR (leucine-rich) repeats. Contains 1 NACHT NLRP8蛋白抗体domain. Database links: Entrez Gene: 126205 Human Omim: 609659 Human SwissProt: Q86W28 Human Unigene: 446925 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NLRP8蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞凋亡 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid