凋亡加强结构域蛋白15样蛋白抗体
规格：1mg/1ml
英文名： NLRC3
别名： CARD15-like; CARD15-like protein; Caterpiller 16.2; Caterpiller protein 16.2; CLR16.2; FLJ00348; NLR family, CARD domain containing 3; Nlrc3; NLRC3_HUMAN; NOD-like receptor C3; NOD3; NOD3 protein; Nuc
分子量： 115kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NLRC3
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
凋亡加强结构域蛋白15样蛋白抗体产品介绍：background: This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Function: May modulate T-cell activation. Decreases the transcription of genes 凋亡加强结构域蛋白15样蛋白抗体that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in peripheral blood mononuclear cells. Similarity: Belongs to the NLRP family. Contains 16 LRR (leucine-rich) repeats. Contains 1 NACHT domain. Database links: Entrez Gene: 197358 Human Entrez Gene: 268857 Mouse Entrez Gene: 287070 Rat SwissProt:凋亡加强结构域蛋白15样蛋白抗体 Q7RTR2 Human SwissProt: Q5DU56 Mouse Unigene: 2061102 Human Unigene: 728268 Human Unigene: 215994 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凋亡加强结构域蛋白15样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 **细胞 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid