突触细胞粘附分子1/突触细胞粘附分子2抗体
规格:1mg/1ml
英文名: NLGN1 + NLGN2
别名: 6330415N05Rik; BB179718; KIAA1070; KIAA1366; MGC107366; MGC45115; MGC67386; mKIAA1070; Neuroligin 1; Neuroligin 2; Neuroligin I; NL1; NL2; Ortholog of human and rat neuroligin 2 NLGN2; OTTHUMP00000211
分子量: NLGN1, 94kD ; NkDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NLGN1 +
交叉反应:Human, Mouse,
细胞定位:细胞膜
突触细胞粘附分子1/突触细胞粘附分子2抗体产品介绍:background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008] Function: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro突触细胞粘附分子1/突触细胞粘附分子2抗体, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Subunit: Interacts with NRXN1, NRXN2 and NRXN3. Interacts with NLGN3. Interacts with AIP1 and PDZRN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Interacts with GOPC. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the type-B carboxylesterase/lipase family. Gene ID: 22871 57555 Database links: Entrez Gene: 22871 Human Entrez Gene: 57555 Human Entrez Gene: 192167 Mouse Entrez Gene: 216856 Mouse Entrez Gene: 116647 Rat Entrez Gene: 117096 Rat Omim: 600568 Human Omim: 606479 Human 突触细胞粘附分子1/突触细胞粘附分子2抗体SwissProt: Q8N2Q7 Human SwissProt: Q8NFZ4 Human SwissProt: Q69ZK9 Mouse SwissProt: Q99K10 Mouse SwissProt: Q62765 Rat SwissProt: Q62888 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触细胞粘附分子1/突触细胞粘附分子2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 神经生物学 细胞粘附分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid