转录因子同源蛋白Nkx2.6抗体
规格：1mg/1ml
英文名： Nkx2.6
别名： CSX2; Homeobox protein NK-2 homolog F; homeobox protein NK2 homolog F; Homeobox protein Nkx-2.6; Homeobox protein Nkx2.6; NK2 homeobox 6; NK2 transcription factor related, locus 6 (Drosophila); NKX2-6
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Nkx2.6
交叉反应：Human, Mouse,
细胞定位：细胞核
转录因子同源蛋白Nkx2.6抗体产品介绍：background: This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011] Function: In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development. Subcellular Location: Nucleus DISEASE: [MIM:217095]: A group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right 转录因子同源蛋白Nkx2.6抗体ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle. Similarity: 转录因子同源蛋白Nkx2.6抗体Belongs to the NK-2 homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 137814 Human Omim: 611770 Human SwissProt: A6NCS4 Human Unigene: 532654 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子同源蛋白Nkx2.6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 发育生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid