细胞核因子抑制因子抗体
规格：1mg/1ml
英文名： NKRF
别名： ITBA4; NF kappa B repressing factor; NFKB repressing factor; NRF; NKRF_HUMAN; Transcription factor NRF.
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NKRF
交叉反应：Human, Dog, Pig, Cow, Horse,
细胞定位：细胞核
细胞核因子抑制因子抗体产品介绍：background: This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] Function: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription细胞核因子抑制因子抗体. Subcellular Location: Nuclear Tissue Specificity: Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney. Similarity: Contains 1 G-patch domain. Contains 1 R3H domain. Gene ID: 细胞核因子抑制因子抗体55922 Database links: Entrez Gene: 55922 Human Entrez Gene: 100684319 Dog Entrez Gene: 100155370 Pig Omim: 300440 Human SwissProt: O15226 Human Unigene: 437084 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞核因子抑制因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid