核转录因子κB抑制作用Ras样蛋白（κB-Ras1）抗体
规格：1mg/1ml
英文名： NKIRAS1
别名： 2400004O09Rik; I kappa B interacting Ras like protein 1; I-kappa-B-interacting Ras-like protein 1; Kappa B Ras 1; Kappa B Ras protein 1; Kappa B-Ras protein 1; KappaB Ras1; KappaB-Ras1; KBRAS 1; KBRAS
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NKIRAS1
交叉反应：Human, Mouse, Rat, Dog, Cat,
细胞定位：细胞浆
核转录因子κB抑制作用Ras样蛋白（κB-Ras1）抗体产品介绍：Function: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Subunit: Interacts with both NF-kappa-B inhibitor alpha (NFKBIA) and beta (NFKBIB) in vitro. However, it probably only interacts with NFKBIB in vivo. Forms a complex with 核转录因子κB抑制作用Ras样蛋白（κB-Ras1）抗体NFKBIB and NF-kappa-B heterodimer (p50/NFKB1 and p65/RELA). Also interacts with c-Rel (REL). Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. Similarity: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. Gene ID: 28512 Database links: Entrez Gene: 28512 Human Entrez Gene: 69721 Mouse Entrez Gene: 305751 Rat Entrez Gene: 核转录因子κB抑制作用Ras样蛋白（κB-Ras1）抗体100002175 Zebrafish Omim: 604496 Human SwissProt: Q9NYS0 Human SwissProt: Q8CEC5 Mouse SwissProt: Q6DGQ1 Zebrafish Unigene: 173202 Human Unigene: 25648 Mouse Unigene: 79630 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核转录因子κB抑制作用Ras样蛋白（κB-Ras1）抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid