烟碱型乙酰胆碱受体α5抗体
规格：1mg/1ml
英文名： CHRNA5
别名： Acetylcholine receptor nicotinic alpha 5 (neuronal); ACHA5_HUMAN; Cholinergic receptor neuronal nicotinic alpha polypeptide 5; Cholinergic receptor nicotinic alpha 5; Cholinergic receptor nicotinic al
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHRNA5
交叉反应：Human, Chicken, Pig, Cow, Horse, Monkey, Chimpanzee,
细胞定位：细胞膜
烟碱型乙酰胆碱受体α5抗体产品介绍：background: The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010] Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Subcellular Location: Cell junction > synapse > postsynaptic cell membrane. Cell membrane. Tissue Specificity: High expression level is found in brain, testis, liver and kidney. Weak expression in 烟碱型乙酰胆碱受体α5抗体spleen, leukocytes, small intestine and colon Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily. Database links: Entrez Gene: 386577 Chicken Entrez Gene: 619369 Chimpanzee Entrez Gene: 282177 Cow Entrez Gene: 1138 Human Omim: 118505 Human SwissProt: P26152 Chicken SwissProt: Q5IS51烟碱型乙酰胆碱受体α5抗体 Chimpanzee SwissProt: Q8SPU7 Cow SwissProt: P30532 Human Unigene: 1614 Human Unigene: 719767 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
烟碱型乙酰胆碱受体α5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid