NHP2核糖核蛋白样蛋白1抗体
规格:1mg/1ml
英文名: NHP2L1
别名: [U4/U6.U5] tri snRNP; 15.5 kD RNA binding protein; High mobility group like nuclear protein 2 homolog 1; hSNU13; NHP2 non histone chromosome protein 2 like 1 (S. cerevisiae); NHP2L 1; NHP2L1; NH2L1_HU
分子量: 14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NHP2L1
交叉反应:Human, Mouse, Dog, Cow, Sheep,
细胞定位:细胞核
NHP2核糖核蛋白样蛋白1抗体产品介绍:background: Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Function: Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri snRNP. It binds to the 5' stem loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. Subunit: Component of the U4/U6-U5 tri-snRNPNHP2核糖核蛋白样蛋白1抗体 complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, NHP2L1, EFTUD2, SART1 and USP39. Interacts with RAD17 and PRPF31. Subcellular Location: Nucleus ?nucleolus. Note: Concentrated in the dense fibrillar component of the nucleolus. Tissue Specificity: Ubiquitous. Similarity: Belongs to the ribosomal NHP2核糖核蛋白样蛋白1抗体protein L7Ae family. Gene ID: 4809 Database links: Entrez Gene: 4809 Human Entrez Gene: 321114 Zebrafish Omim: 601304 Human SwissProt: P55769 Human Unigene: 182255 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NHP2核糖核蛋白样蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 表观遗传学
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid