核转录因子YC抗体
规格:1mg/1ml
英文名: NFYC
别名: CAAT box DNA binding protein subunit C; CAAT box DNA-binding protein subunit C; CBF C; CBFC; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; DKFZp667G242; FLJ45775; H
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NFYC
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
核转录因子YC抗体细胞定位:细胞核
产品介绍:background: This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] Function: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin 核转录因子YC抗体and beta-actin genes. Subcellular Location: Nucleus. Similarity: Belongs to the NFYC/HAP5 subunit family. Database links: Entrez Gene: 419642 Chicken Entrez Gene: 534003 Cow Entrez Gene: 475312 Dog Entrez Gene: 100715361 Guinea pig Entrez Gene: 100053895 Horse Entrez Gene: 4802 Human Entrez Gene: 18046 Mouse Entrez Gene: 25337 Rat Entrez Gene: 323445 Zebrafish Omim: 605344 Human核转录因子YC抗体 SwissProt: Q5E9X1 Cow SwissProt: Q13952 Human SwissProt: P70353 Mouse SwissProt: Q62725 Rat Unigene: 713051 Human Unigene: 435590 Mouse Unigene: 477613 Mouse Unigene: 1457 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核转录因子YC抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid