核转录因子YB抗体
规格：1mg/1ml
英文名： NFYB
别名： CAAT box DNA binding protein subunit B; CBF A; CBF B; CCAAT binding transcription factor subunit A; HAP 3; HAP3; NF Y protein chain B; NF YB; NFYB; Nuclear transcription factor Y beta; Nuclear transcr
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NFYB
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Zebrafish, Xenopus laevis.
细胞定位：细胞核
核转录因子YB抗体产品介绍：background: The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008] Function: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. Subcellular 核转录因子YB抗体Location: Nucleus. Similarity: Belongs to the NFYB/HAP3 subunit family. Database links: Entrez Gene: 396205 Chicken Entrez Gene: 614382 Cow Entrez Gene: 4801 Human Entrez Gene: 18045 Mouse Entrez Gene: 100157587 Pig Entrez Gene: 25336 Rat Entrez Gene: 399126 Xenopus laevis Omim: 189904 Human SwissProt: P25207 Chicken SwissProt: Q32KW0 Cow SwissProt: P25208 Human SwissProt: P63139 Mouse 核转录因子YB抗体SwissProt: P63140 Rat SwissProt: Q5FVT0 Rat SwissProt: 100157587 Xenopus laevis SwissProt: P25211 Xenopus laevis Unigene: 84928 Human Unigene: 245998 Mouse Unigene: 90077 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核转录因子YB抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid