半胱氨酸脱硫酶NFS1抗体
规格：1mg/1ml
英文名： NFS1
别名： Cysteine desulfurase; Cysteine desulfurase, mitochondrial; HUSSY 08; IscS; mitochondrial; NFS1; NFS1 nitrogen fixation 1; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NFS1_HUMAN; NIFS; nitrogen f
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NFS1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, Saccharomyces cerevisiae
细胞定位：细胞核 细胞浆
半胱氨酸脱硫酶NFS1抗体产品介绍：background: Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010] Function: Catalyzes the removal of 半胱氨酸脱硫酶NFS1抗体elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor. Subcellular Location: Cytoplasm. Nucleus and Mitochondrion. Tissue Specificity: Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas. Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. Database links: Entrez Gene: 9054 Human Entrez Gene: 18041 Mouse Entrez Gene: 84594 Rat Omim: 603485 Human 半胱氨酸脱硫酶NFS1抗体SwissProt: Q9Y697 Human SwissProt: Q9Z1J3 Mouse SwissProt: Q99P39 Rat Unigene: 194692 Human Unigene: 283604 Mouse Unigene: 3151 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
半胱氨酸脱硫酶NFS1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid