神经细胞钙结合蛋白抗体
规格：1mg/1ml
英文名： NECAB3
别名： Neuronal calcium-binding protein; amyloid beta (A4) precursor protein binding, family A, member 2 binding protein; Amyloid beta A4 protein binding family A member 2 binding protein; Amyloid beta A4 pr
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NECAB3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cat,
神经细胞钙结合蛋白抗体细胞定位：
产品介绍：background: The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Inhibits the interaction of APBA2 with beta-amyloid precursor protein (APP), and hence allows formation of beta-amyloid. Subcellular Location: Golgi apparatus.神经细胞钙结合蛋白抗体 Tissue Specificity: Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas. Post-translational modifications: Phosphorylated by NEK2. Similarity: Contains 1 ABM domain. Contains 1 EF-hand domain. Database links: Entrez Gene: 63941神经细胞钙结合蛋白抗体 Human Entrez Gene: 311562 Rat Omim: 612478 Human SwissProt: Q96P71 Human Unigene: 516986 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产神经细胞钙结合蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid