三叶肽因子2抗体
规格:1mg/1ml
英文名: TFF2
别名: Trefoil factor2; mSP; SP; Spasmolytic polypeptide; Spasmolysin; SML 1; SML1; spasmolytic protein 1; TFF 2; trefoil factor 2 (spasmolytic protein 1); TFF 2; TFF2_HUMAN; Trefoil factor 2; Trefoil factor
分子量: 12/14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TFF2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:分泌型蛋白
三叶肽因子2抗体产品介绍:background: Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. Function: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly 三叶肽因子2抗体by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity). Subcellular Location: Secreted. Tissue Specificity: Stomach. Similarity: Contains 2 P-type (trefoil) domains. Gene ID: 7032 Database links: Entrez Gene: 7032 三叶肽因子2抗体Human Omim: 182590 Human SwissProt: Q03403 Human Unigene: 2979 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 三叶肽可能使黏膜凝胶产生更大的稳定性,使胃黏膜对各种损伤因子的防御能力增强。三叶肽在诱导上皮修复上的直接作用,可用于许多胃肠道**。它作为辅助剂或取代皮质类固醇或其他**抑制剂,在溃疡病及炎症性肠病的**上可能是一个突破。
三叶肽因子2抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 生长因子和**
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid