E3泛素连接酶蛋白NEURL2抗体
规格：1mg/1ml
英文名： NEURL2
别名： Neuralized like protein 2.
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NEURL2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位：细胞浆
E3泛素连接酶蛋白NEURL2抗体产品介绍：background: This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013] Function: Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controlsE3泛素连接酶蛋白NEURL2抗体 the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma By similarity. Subcellular Location: Cytoplasmic Tissue Specificity: Expressed specifically in skeletal and cardiac muscles. Similarity: Probable component the ECS(NEURL2) E3 ubiquitin-protein ligase complex consisting of TCEB2/Elongin B, TCEB1/Elongin C, CUL5, RBX1 and NEURL2. Interacts with CTNNB1 ByE3泛素连接酶蛋白NEURL2抗体 similarity. Database links: Entrez Gene: 140825 Human Entrez Gene: 415115 Mouse Entrez Gene: 311633 Rat Omim: 608597 Human SwissProt: Q9BR09 Human SwissProt: Q9D0S4 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
E3泛素连接酶蛋白NEURL2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 激酶和磷酸酶 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid