突触核膜蛋白3抗体
规格:1mg/1ml
英文名: Nesprin 3
别名: C14orf49; Chromosome 14 open reading frame 49; FLJ25605; MGC75267; Nesp3; Nesprin3; Nesprin-3; NET53; Nuclear Envelope Spectrin Repeat Protein 3; Spectrin Repeat Containing, Nuclear Envelope Family Me
分子量: 68kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Nesprin
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
突触核膜蛋白3抗体产品介绍:Function: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Subcellular Location: Nucleus outer membrane. 突触核膜蛋白3抗体Located at the rough reticulum endoplasmic (RER) in some cells. Similarity: Belongs to the nesprin family. Contains 1 KASH domain. Contains 2 spectrin repeats. Database links: Entrez Gene: 490843 Dog Entrez Gene: 100053652 Horse Entrez Gene: 161176 Human Entrez Gene: 212073 Mouse Entrez Gene: 100525411 Pig Entrez Gene: 299356 Rat Omim: 610861 Human SwissProt: Q6ZMZ3 Human SwissProt:突触核膜蛋白3抗体 Q4FZC9 Mouse Unigene: 354645 Human Unigene: 212688 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触核膜蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 神经生物学 信号转导 结合蛋白 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid