丝氨酸/苏氨酸蛋白激酶Nek11抗体
规格：1mg/1ml
英文名： NEK11
别名： 4932416N14Rik; FLJ23495; NEK11; NEK11_HUMAN; NEK11S/L; Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a) related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NIMA r
分子量： 54 and 74kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NEK11
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
丝氨酸/苏氨酸蛋白激酶Nek11抗体产品介绍：background: This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009] Function: Possible role in S-phase checkpoint mechanism. Subcellular Location: Nucleus. Nucleus > nucleolus. Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells. 丝氨酸/苏氨酸蛋白激酶Nek11抗体Tissue Specificity: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. Post-translational modifications: Phosphorylated. Similarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily丝氨酸/苏氨酸蛋白激酶Nek11抗体. Contains 1 protein kinase domain. Gene ID: 79858 Database links: Entrez Gene: 79858 Human Entrez Gene: 208583 Mouse Omim: 609779 Human SwissProt: Q8NG66 Human SwissProt: Q8C0Q4 Mouse Unigene: 657336 Human Unigene: 347509 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝氨酸/苏氨酸蛋白激酶Nek11抗体产品应用：WB=1:100-500 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid