垂体特异性同源因子抗体
规格：1mg/1ml
英文名： PROP1
别名： CPHD2; Homeobox protein prophet of Pit 1; OTTHUMP00000161487; paired-like homeodomain transcription factor; Pituitary specific homeodomain factor; PROP 1; PROP paired like homeobox 1; prophet of Pit1.
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PROP1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
垂体特异性同源因子抗体细胞定位：细胞核
产品介绍：background: This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011] Function: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. Subcellular Location:垂体特异性同源因子抗体 Nucleus DISEASE: Combined pituitary hormone deficiency is defined as the impaired production of growth hormone and one or more of the other five anterior pituitary hormones. CPHD2 is characterized by pleiotropic deficiencies of growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, prolactin and adrenocorticotropic hormone. Similarity: Belongs to the paired homeobox family. Contains 1 homeobox DNA-binding domain. Gene ID: 5626 Database links: Entrez Gene: 5626 Human Entrez Gene: 266738 Rat Omim: 垂体特异性同源因子抗体601538 Human SwissProt: O75360 Human Unigene: 158301 Human Unigene: 86655 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
垂体特异性同源因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid