肌球蛋白3A抗体
规格：1mg/1ml
英文名： MYO3A
别名： deafness, autosomal recessive 30; DFNB30; Myo3a; MYO3A_HUMAN; Myosin IIIA; Myosin-IIIa.
分子量： 186kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MYO3A
交叉反应：Human, Mouse,
细胞定位：细胞浆
产肌球蛋白3A抗体品介绍：background: The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008] Function: Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing. Subcellular Location: Cytoplasm, cytoskeleton. Tissue 肌球蛋白3A抗体Specificity: Strongest expression in retina, retinal pigment epithelial cells, cochlea and pancreas. DISEASE: Deafness, autosomal recessive, 30 Similarity: In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. 肌球蛋白3A抗体Contains 3 IQ domains. Contains 1 myosin head-like domain. Contains 1 protein kinase domain. Gene ID: 53904 Database links: Entrez Gene: 53904 Human Omim: 606808 Human SwissProt: Q8NEV4 Human Unigene: 662630 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌球蛋白3A抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid