视黄酸受体应答蛋白1抗体
规格:1mg/1ml
英文名: RARRES1
别名: Retinoic acid receptor responder protein 1; RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein; TIG1_HUMAN.
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RARRES1
交叉反应:Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位:
视黄酸受体应答蛋白1抗体产品介绍:background: RARRES1 (Retinoic acid receptor responder 1) is a retinoid-regulated gene whose expression is down-regulated through DNA hypermethylation. It was originally identified as a target gene that was induced by the synthetic retinoid tazarotene (AGN 190168). Its expression is upregulated by retinoic acid receptor-specific, but not by retinoid X receptor-specific retinoids. Although the function of RARRES1 is not entirely clear, it is thought to act as a tumor suppressor of a variety of human cancers since inactivation of RARRES1 is involved in the malignant progression of prostate cancer. It may also function as a cell adhesion molecule. Additionally,视黄酸受体应答蛋白1抗体 RARRES1 may also have protease inhibitor activity and inhibit the degradation of extracellular 视黄酸受体应答蛋白1抗体matrix. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Similarity: Belongs to the protease inhibitor I47 (latexin) family. Gene ID: 5918 Database links: Entrez Gene: 5918 Human Omim: 605090 Human SwissProt: P49788 Human Unigene: 131269 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
视黄酸受体应答蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid