肌球蛋白重链1抗体
规格：1mg/1ml
英文名： MYO1A
别名： BBM I; BBM-I; BBMI; Brush border myosin I; DFNA48; MIHC; MYHL; Myo1a; MYO1A_HUMAN; Myosin I heavy chain; Myosin, heavy polypeptide like (100kD); Myosin-IA.
分子量： 118kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MYO1A
交叉反应：Human, Mouse, Chicken, Cow,
细胞定位：细胞浆
肌球蛋白重链1抗体产品介绍：background: This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011] Function: Involved in directing the movement of organelles along actin filaments. 肌球蛋白重链1抗体DISEASE: Defects in MYO1A are the cause of deafness autosomal dominant type 48 (DFNA48) [MIM:607841]. DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to 肌球蛋白重链1抗体the brain, or the area of the brain that receives sound information. Similarity: Contains 3 IQ domains. Contains 1 myosin head-like domain. Database links: Entrez Gene: 4640 Human Entrez Gene: 432516 Mouse Omim: 601478 Human SwissProt: Q9UBC5 Human SwissProt: O88329 Mouse Unigene: 5394 Human Unigene: 90450 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌球蛋白重链1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid