血管内皮生长因子B抗体
规格：1mg/1ml
英文名： VEGF-B
别名： Vascuoar endothelial growth factor B; Vegfb; VEGF-B; VEGF B; VEGFB 167; Vrf; VEGF-related factor; VRF; VEGFB_HUMAN.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VEGFB
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞外基质 分泌型蛋白
血管内皮生长因子B抗体产品介绍：background: This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] Function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Subunit: Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Subcellular Location: Secreted. Note=Secreted but remains associated血管内皮生长因子B抗体 to cells or to the extracellular matrix unless released by heparin. Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Post-translational modifications: VEGF-B186 is O-glycosylated. Similarity: Belongs 血管内皮生长因子B抗体to the PDGF/VEGF growth factor family. Gene ID: 7423 Database links: Entrez Gene: 7423 Human Entrez Gene: 22340 Mouse Entrez Gene: 89811 Rat Omim: 601398 Human SwissProt: P49765 Human SwissProt: P49766 Mouse SwissProt: O35485 Rat Unigene: 78781 Human Unigene: 15607 Mouse Unigene: 198550 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：血管内皮生长因子B抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 生长因子和** 激酶和磷酸酶 细胞膜受体 血管内皮细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid