C myc结合蛋白抗体
规格：1mg/1ml
英文名： MYCBP
别名： AMY 1; AMY-1; AMY1; Associate of myc 1; C myc binding protein; C-Myc-binding protein; Cmyc binding protein; MYCBP; MYCBP_HUMAN.
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MYCBP
交叉反应：Human, Mouse, Chicken, Pig, Cow, Rabbit,
细胞定位：细胞核 细胞浆
C myc结合蛋白抗体产品介绍：background: The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011] Function: May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. Subcellular Location: Cytoplasm. Nucleus. Mitochondrion. Translocates into the nucleus in the S phase of the cell cycle C myc结合蛋白抗体upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1. Tissue Specificity: Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung. Similarity: Belongs to the AMY1C myc结合蛋白抗体 family. Gene ID: 26292 Database links: Entrez Gene: 26292 Human Entrez Gene: 539291 Cow Entrez Gene: 56309 Mouse Omim: 606535 Human SwissProt: Q2TBP7 Cow SwissProt: Q99417 Human SwissProt: Q9EQS3 Mouse Unigene: 591506 Human Unigene: 446553 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：C myc结合蛋白抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞周期蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid