基质金属蛋白酶-8/胶原酶2抗体
规格：1mg/1ml
英文名： MMP8
别名： Matrilysin/matrix metalloproteinases-8; CLG 1; CLG1; Collagenase II; Collagenase 2; Collagenase neutrophil; HNC; Matrix metalloprotease 8; MMP8; MMP 8; MMP-8; Neutrophil collagenase; PMNL CL; PMNL col
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MMP8
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞外基质 分泌型蛋白
基质金属蛋白酶-8/胶原酶2抗体产品介绍：background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes 基质金属蛋白酶-8/胶原酶2抗体which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] Function: Can degrade fibrillar type I, II, and III collagens. Subcellular Location: Cytoplasmic granule. Secreted, extracellular space, extracellular matrix (Probable). Note=Stored in intracellular granules. Tissue Specificity: Neutrophils. Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. 基质金属蛋白酶-8/胶原酶2抗体Gene ID: 4317 Database links: Entrez Gene: 4317 Human Entrez Gene: 17394 Mouse Entrez Gene: 63849 Rat Omim: 120355 Human SwissProt: P22894 Human SwissProt: O70138 Mouse SwissProt: O88766 Rat Unigene: 161839 Human Unigene: 16415 Mouse Unigene: 44474 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
基质金属蛋白酶-8/胶原酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid