肌球蛋白结合蛋白C抗体
规格:1mg/1ml
英文名: MYBPC2
别名: C protein, skeletal muscle fast isoform; C-protein; Fast MyBP C; Fast MyBP-C; MGC163408; MYBPC; Mybpc2; MYBPCF; Myosin binding protein C, fast type; Myosin-binding protein C, fast-type; MYPC2_HUMAN; s
分子量: 128kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MYBPC2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位:细胞浆
肌球蛋白结合蛋白C抗体产品介绍:background: This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively. [provided by RefSeq, Jul 2012] Function: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may 肌球蛋白结合蛋白C抗体modulate muscle contraction or may play a more structural role. Similarity: Belongs to the immunoglobulin superfamily. MyBP family. Contains 3 fibronectin type-III domains. Contains 7 Ig-like C2-type (immunoglobulin-like) domains. Database links: Entrez Gene:肌球蛋白结合蛋白C抗体 4606 Human Entrez Gene: 233199 Mouse Entrez Gene: 292879 Rat Omim: 160793 Human SwissProt: Q14324 Human SwissProt: Q5XKE0 Mouse Unigene: 85937 Human Unigene: 358888 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌球蛋白结合蛋白C抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 结合蛋白 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid