毒蕈碱型乙酰胆碱受体M5抗体
规格：1mg/1ml
英文名： CHRM5
别名： Acetylcholine receptor muscarinic 5; AChR M5; CHKM5MR; Cholinergic receptor muscarinic 5; Chrm 5; CHRM5; HM 5; HM5; m5; M5R; MGC41838.
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHRM5
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
毒蕈碱型乙酰胆碱受体M5抗体产品介绍：background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008] Function: Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, 毒蕈碱型乙酰胆碱受体M5抗体replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. Subcellular Location: Membrane; multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. Gene ID: 1133 Database links: Entrez Gene: 1133 Human Entrez Gene: 213788 Mouse 毒蕈碱型乙酰胆碱受体M5抗体Entrez Gene: 53949 Rat Omim: 118496 Human SwissProt: P08912 Human SwissProt: A2AHU3 Mouse SwissProt: P08911 Rat Unigene: 297624 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产毒蕈碱型乙酰胆碱受体M5抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid