钙粘蛋白相关家庭成员5/μ-protocadherin抗体
规格:1mg/1ml
英文名: MUPCDH
别名: Cadherin-related family member 5; Cdhr5; CDHR5_HUMAN; FLJ 20219; FLJ20219; MU-PCDH; Mu-protocadherin; MUCDHL; MUCDHL-ALT; MUCDHL-FL; Mucin and cadherin-like protein; mucin-like protocadherin.
分子量: 85kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MUPCDH
交叉反应:Human,
细胞定位:细胞膜
钙粘蛋白相关家庭成员5/μ-protocadherin抗体产品介绍:background: This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010] Function: Acts as a calcium-dependent cell adhesion protein. Subcellular Location: Cell membrane. Tissue Specificity:钙粘蛋白相关家庭成员5/μ-protocadherin抗体 Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in ***** small intestine and colon. Isoform 2 is highly expressed in fetal liver. Post-translational modifications: N- and O-glycosylated. Similarity: Contains 4 cadherin domains.钙粘蛋白相关家庭成员5/μ-protocadherin抗体 Gene ID: 53841 Database links: Entrez Gene: 53841 Human Entrez Gene: 101138146 Gorilla Entrez Gene: 100410617 Marmoset (common) Entrez Gene: 100461892 Orangutan Omim: 606839 Human SwissProt: Q9HBB8 Human Unigene: 165619 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙粘蛋白相关家庭成员5/μ-protocadherin抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞粘附分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid