NDUFS8蛋白抗体
规格：1mg/1ml
英文名： NDUFS8
别名： CI 23kD; CI-23kD; Complex I 23kD; Complex I-23kD; EC 1.6.5.3; EC 1.6.99.3; Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mito
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NDUFS8
交叉反应：Human,
细胞定位：
NDUFS8蛋白抗体产品介绍：background: This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010] Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for theNDUFS8蛋白抗体 enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone. Subcellular Location: Mitochondrion. DISEASE: Defects in NDUFS8 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions. Similarity: Belongs to the complex I 23 kDa subunit family. Contains 2 4Fe-4S ferredoxin-typeNDUFS8蛋白抗体 domains. Gene ID: 4728 Database links: Entrez Gene: 4728 Human Entrez Gene: 287027 Cow Entrez Gene: 225887 Mouse Entrez Gene: 293652 Rat Omim: 602141 Human SwissProt: Q0MQI3 Chimpanzee SwissProt: P42028 Cow SwissProt: Q60HE3 Cynomolgus Monkey SwissProt: O00217 Human SwissProt: Q8K3J1 Mouse SwissProt: P0CB97 Orangutan Unigene: 90443 Human Unigene: 44227 Mouse Unigene: 3373 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：NDUFS8蛋白抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit