NADH氧化还原酶辅酶6抗体
规格:1mg/1ml
英文名: NDUFA6
别名: LYRM6; NADHB14; Complex I-B14; CI-B14; LYR motif-containing protein 6; NADH-ubiquinone oxidoreductase B14 subunit.
分子量: 18kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NDUFA6
交叉反应:Human, Mouse, Rat, Cow, Chimpanzee, Rhesus monkey, Gorilla
细胞定位:
NADH氧化还原酶辅酶6抗体产品介绍:background: NDUFA6 is a 128 amino acid protein that localizes to the matrix side of the mitochondrial membrane and belongs to the complex I LYR family. Existing as a subunit of the multi-protein membrane respiratory chain NADH dehydrogenase complex (Complex I), NDUFA6 functions as an accessory protein that facilitates the transfer of electrons from NADH to the respiratory chain. The gene encoding NDUFA6 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH NADH氧化还原酶辅酶6抗体dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Subunit: Mammalian complex I is composed of 45 different subunits. Subcellular Location: Mitochondrion inner membrane. Similarity: Belongs to the complex I LYR family. NADH氧化还原酶辅酶6抗体Database links: Entrez Gene: 458981 Chimpanzee Entrez Gene: 327670 Cow Entrez Gene: 101135077 Gorilla Entrez Gene: 4700 Human Entrez Gene: 67130 Mouse Omim: 602138 Human SwissProt: Q0MQA5 Chimpanzee SwissProt: Q02366 Cow SwissProt: Q0MQA4 Gorilla SwissProt: P56556 Human SwissProt: Q9CQZ5 Mouse Unigene: 274416 Human Unigene: 27570 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NADH氧化还原酶辅酶6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid