突触结合蛋白3抗体
规格：1mg/1ml
英文名： SYT3
别名： Synaptotagmin 3; Synaptotagmin-3; SYT 3; SYT-3; Synaptotagmin3; synaptotagmin III; SIII; DKFZp761O132; SytIII; AI385753; P65; SVP65; SYT3_HUMAN.
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human synaptot
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
突触结合蛋白3抗体产品介绍：background: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can 突触结合蛋白3抗体bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Subunit: Homodimer. Can also form heterodimers with SYT6. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Similarity: Belongs to the synaptotagmin family. 突触结合蛋白3抗体Contains 2 C2 domains. Gene ID: 84258 Database links: Entrez Gene: 84258 Human Entrez Gene: 20981 Mouse Entrez Gene: 25731 Rat Omim: 600327 Human SwissProt: Q9BQG1 Human SwissProt: O35681 Mouse SwissProt: P40748 Rat Unigene: 515554 Human Unigene: 4824 Mouse Unigene: 48884 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触结合蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid