NDUF3蛋白抗体
规格：1mg/1ml
英文名： NDUF3
别名： C3orf60; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; NDUF3_HUMAN; ndufaf3.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
NDUF3蛋白抗体**原：KLH conjugated synthetic peptide derived from human NDUF3
交叉反应：Human, Rat,
细胞定位：细胞核
产品介绍：background: This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2009] Function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Subunit: Interacts with NDUFAF4, NDUFS2 and NDUFS3. Subcellular Location: Nucleus. Mitochondrion inner membrane. DISEASE: Defects in NDUFAF3 are a cause of mitochondrial complexNDUF3蛋白抗体 I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to *****-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and someNDUF3蛋白抗体 forms of Parkinson disease. Database links: Entrez Gene: 25915 Human Entrez Gene: 56769 Rat Omim: 612911 Human SwissProt: Q9BU61 Human SwissProt: O08776 Rat Unigene: 31387 Human Unigene: 40118 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NDUF3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 转录调节因子 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid