NDST3蛋白抗体
规格：1mg/1ml
英文名： NDST3
别名： Bifunctional heparan sulfate N deacetylase/N sulfotransferase 3; Glucosaminyl N deacetylase/N sulfotransferase 3; Glucosaminyl N-deacetylase/N-sulfotransferase 3; Heparan sulfate N-sulfotransferase 3;
分子量： 101kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NDST3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位：细胞浆
NDST3蛋白抗体产品介绍：background: This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq, Nov 2008] Function: Essential bifunctional enzyme that catalyzes both the N-deacetylation andNDST3蛋白抗体 the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in brain, kidney, liver, fetalNDST3蛋白抗体 and ***** lung, ***** pancreas, placenta, fetal spleen and fetal thymus. Not detected in *****/ fetal heart and skeletal muscle. Similarity: Belongs to the sulfotransferase 1 family. NDST subfamily. Database links: Entrez Gene: 9348 Human Entrez Gene: 83398 Mouse Entrez Gene: 295430 Rat Omim: 603950 Human SwissProt: O95803 Human SwissProt: Q9EQH7 Mouse Unigene: 480596 Human Unigene: 443908 Mouse Unigene: 487979 Mouse Unigene: 228192 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NDST3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid