蛋白激酶锚定蛋白样蛋白2抗体
规格：1mg/1ml
英文名： NBEAL2
别名： BDPLT4; GPS; NBEAL2; NBEL2_HUMAN; Neurobeachin-like protein 2; UNQ253/PRO290.
分子量： 303kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NBEAL2
交叉反应：Human, Mouse, Rat, Pig, Horse, Rabbit,
细胞定位：细胞浆
蛋白激酶锚定蛋白样蛋白2抗体产品介绍：background: The protein encoded by this gene contains a beige and Chediak-Higashi (BEACH) domain and multiple WD40 domains, and may play a role in megakaryocyte alpha-granule biogenesis. Mutations in this gene are a cause of gray platelet syndrome. [provided by RefSeq, Dec 2011] Function: Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis. Subcellular Location: Endoplasmic reticulum. Tissue Specificity: Expressed in megakaryocytes. DISEASE: Gray platelet syndrome (GPS) [MIM:139090]: A rare platelet disorder characterized by a蛋白激酶锚定蛋白样蛋白2抗体selective deficiency in the number and contents of platelet alpha-granules. It is associated with mild to moderate bleeding tendency and moderate thrombocytopenia. The platelets are enlarged and have a gray appearance on light microscopy of蛋白激酶锚定蛋白样蛋白2抗体 Wright-stained peripheral blood smears due to decreased granules. Similarity: Belongs to the WD repeat neurobeachin family. Contains 1 BEACH domain. Contains 5 WD repeats. Gene ID: 23218 Database links: Entrez Gene: 23218 Human Omim: 614169 Human SwissProt: Q6ZNJ1 Human Unigene: 437043 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白激酶锚定蛋白样蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid